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  • Genealogies

    The relationship between genes (i.e. their genealogy) can be described and manipulated.  

  • For example, this represents a rooted genealogy that relates genes {a...h}:

  • [Graphics:../Images/index_gr_1.gif]
  • This plots the genealogy:

  • [Graphics:../Images/index_gr_2.gif]

    [Graphics:../Images/index_gr_3.gif]

  • Random genealogies can be produced according to the coalescent process:

  • [Graphics:../Images/index_gr_4.gif]

    [Graphics:../Images/index_gr_5.gif]

    Genealogies can be inferred from a data matrix under the infinite-sites model.  The Griffiths-Tavare algorithm is implemented, in both stochastic and exact forms.

  • For example, this gives the probability of observing a certain configuration of mutations as a function of the scaled mutation rate:

  • [Graphics:../Images/index_gr_6.gif]
    [Graphics:../Images/index_gr_7.gif]


    Converted by Mathematica      April 16, 2002

    This site is no longer maintained and has been left for archival purposes

    Text and links may be out of date

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